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Health News: Interval Training, Plus The Benefits of Fat

•Interval training just got another boost from the New York Times:

[Researcher] Gibala...had a group of college students...ride a stationary bike at a sustainable pace for between 90 and 120 minutes. Another set of students grunted through a series of short, strenuous intervals: 20 to 30 seconds of cycling at the highest intensity the riders could stand. After resting for four minutes, the students pedaled hard again for another 20 to 30 seconds, repeating the cycle four to six times (depending on how much each person could stand), "for a total of two to three minutes of very intense exercise per training session," Gibala says.

Each of the two groups exercised three times a week. After two weeks, both groups showed almost identical increases in their endurance (as measured in a stationary bicycle time trial), even though the one group had exercised for six to nine minutes per week, and the other about five hours. Additionally, molecular changes that signal increased fitness were evident equally in both groups. ... In other words, six minutes or so a week of hard exercise (plus the time spent warming up, cooling down, and resting between the bouts of intense work) had proven to be as good as multiple hours of working out for achieving fitness.

So, as fitness geeks have been saying for a few years now, high-intensity training confers many of the benefits of long-distance work without requiring hours and hours of plodding and pounding.  This is great news for people who find long-distance work boring, and/or are short on time generally, and/or don't mind a little pain and suffering in their pursuit of fitness. 

To my eye, there's something slightly amiss here, though:  'fitness' here is defined as leanness, exceptional endurance, and some adaptations in the mitochondria of muscle cells (check out the whole article).  To my mind, these don't cover the entire spectrum of what constitutes good health and exceptional fitness:  there's nothing about flexibility, strength, joint health, posture, agility, power, balance, athleticism, or any other of the myriad markers of fitness in this study.  

Moreover, there's nothing about which system--if any--is truly sustainable.  Does interval training cause injury?  Does steady-state work cause repetitive-stress fractures?

As always, in measuring fitness, one has to ask, fit for what?  As long as the idea of 'fitness' is reduced to one or two markers, there will always be something missing from the picture.

•Here's another thought-provoker:  that obesity may have allowed us to fight off TB back in the day:


A provocative new hypothesis suggests that in some people, fat not only stores energy but also revs up the body’s immune system. This subgroup may have enjoyed a survival advantage in the 1800s, when people were plagued by a disease that decimated Europe: tuberculosis.


But the heightened immune response that helped some overweight adults survive tuberculosis is now an "evolutionary anachronism" that has outlived its usefulness, said Dr. Jesse Roth...

"Fat is not simply a collection of calories, it is acting like a part of the innate immune system," said Dr. Roth, an investigator at the Feinstein Institute for Medical Research in Manhasset, N.Y. "But this immune system has a downside."

...Yet the question Dr. Roth tries to answer has baffled scientists. The "thrifty gene" hypothesis suggests that evolution favored those who could store fat reserves that helped them withstand lean times, like periodic famines and food shortages.

But that does not explain why body fat carries so many drawbacks, setting off inflammation and metabolic disorders like insulin resistance, high cholesterol and atherosclerosis.

I'm no fancy evolutionary biologist, but I imagine that real obesity such as is epidemic today is probably a fairly modern phenomenon, simply because at no time else in history has such a large portion of the population been so sedentary AND had such easy access to calorie-dense food. 

There was a time, after all, when feeding oneself cost calories.  It wasn't just a matter of wheeling your SUV through the drive-thru:  you had to track down an animal or plant a crop.  The food you consumed was a reward for the physical labor of finding or hunting or growing that food (could this be part of why a post-workout meal tastes so good?).

Perhaps the gene for obesity was indeed effective in fighting off certain diseases and for keeping one alive during lean periods.  But back in the caveman days when these genes were evolving, I imagine that food was scarce enough that even Joe Caveman with the "fat" gene never really got fat.  He would have had to be exceptionally active by today's standards just to stay alive, after all:  running down prey and avoiding predators, migrating to fertile areas during winter months, and later, planting crops and tending fields.  Sitting around on the couch--or the comfy rock, perhaps--just wasn't an option. 

So back then we might have had a bunch of hairy strong guys carrying the fat gene who weren't fat.  They got all the disease-fighting, life-sparing benefits of having a 'thrifty' metabolism but weren't saddled with all the downsides of actuelly being fat which are so prevalent today.  So they lived long enough to reproduce, and eventually, their genes spawned our current generation of couch-dwelling, fast-food snarfing denizens.  

Anyone else have a theory?

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part of the innate immune response is inflammation

Of course this is why you run a fever when you are sick and why eating in of itself is inflammatory. The body is preparing itself to expel foreign pathogens.

Perhaps fat stores rev up the body’s immune system by increasing inflammation. Useful in the feast or famine days of an Inconvenient food supply— when the inflammation is not chronic— not so useful in the drivethru burrito and mocciotto days.

Hey its the fat guy who started a diet log on this site a few months ago then quit. The diet is still on its just the online log was just taking too much time. I’ve lost all of 10lbs in three months— not exactly warp speed weight loss— but its better than nothing. Although I always find it odd that the weight comes off in increments not linearly— frustrating. The knee ended up being a problem with knee cap tracking (curses IT band) and its probably going to be a long road of foam rolling and right leg exercises to regain muscular and functional symmetry between the two limbs. My left leg was an inch and half larger an my right! Should have gotten it looked at sooner. The YWTL Diesel crew stuff in addition to a bunch of external rotation work did wonders for my bum shoulder. Focusing on those not-so-sexy exercises has led to a big increase in the number of chin ups I can do in a workout session. Up to a meager 18 now from the abysmal 2 a couple of months ago— I had to laugh because your prescription to do a couple of reps every time you pass the bar has been my mode of doing them lately. It works— I’m slowly adding in pull ups as I get better, these can be uncomfortable unless I’m very well warmed up.

by vman on Jun 25, 2009 8:59 AM EDT reply actions  

Thanks for the report!

10 lbs in 3 months = 40 lbs in a year, 80 lbs in 2 years. Not a bad rate of loss. Plus you’re building some muscle as you work, so you’re probably losing more fat than the scale indicates.

Glad the shoulders are working better. Hang in there on the low-body rehab stuff; it will improve! I had a knee injury about 6 weeks ago and am still working around it; takes time for sure. Keep the hips and ankles mobile and strong.

Keep reporting back.

by Andrew Heffernan on Jun 25, 2009 1:59 PM EDT up reply actions  

Inflammation

Inflammation is the body’s defensive response against pathogens, and is a vital part of the immune system. Allergies are simply the body’s immune system misfiring an inflammation response against non-pathogens.

My hypothesis is that the immune system is a little overreactive in causing inflammatory responses to some foods; in today’s never-ending supply of food, this tiny bit of overreacting compounds over time, and you slowly but surely develop that beer gut. I highly doubt that stored fat is preventative against anything but cold and starvation.

by ectonoob on Jun 25, 2009 3:22 PM EDT up reply actions  

Obesity and TB theory

I would bet that the researches looking at those TB health records from the 1800s were using a simple Body Mass Index calculation in reaching their conclusion that the overweight tended to be more successful in battling TB infection. I would submit that, especially in the 19th century, when people were much more physically active, a good proportion of those high-BMI patients were actually strapping physical specimens whose excess weight was attributable to muscles gained from physical labor rather than snack foods consumed while coach surfing.

It’s a well-known fact that people who are thin and frail (underweight) don’t fare as well when fighting serious illness. Most everyone will lose substantial amounts of weight (lean mass and fat mass) when seriously ill. You get below a certain amount level of overall lean mass and your fate is sealed. So, generally speaking, those with more mass going into an illness (not necessarily more fat mass) can fight that illness longer and harder than those who went in with little mass to spare. I think it’s that, not some immunity benefit conferred by fat, that showed up in the researchers’ results.

by BobParr on Jun 25, 2009 11:31 AM EDT reply actions  

Unreliability of BMI

Very true. Most fit guys are high-end normal or low-end overweight by the BMI scale. And the skinny-fat crowd gets a free pass—their BMI is perfect! As with any other measure, it only tells part of the story. Thanks as always for the post—A

by Andrew Heffernan on Jun 25, 2009 2:01 PM EDT up reply actions  

Caveman fatness

For the vast majority of time H. Sapiens has existed (160k years) nobody really lived long enough to suffer the lethally negative effects of getting fat…even if they somehow did manage to get fat. During most of human history most folks have died before age 30. Nobody lived long enough to die from type II diabetes, athereosclerosis, hypertension, coronary artery disease.
Tuberculosis is caused by a particularly slow-growing bacterium (“mycobacterium”). It takes years to kill. Hence the lay term for it was “the consumption”. Just sits in your lungs growing away. Most conspicuous symptom is a nasty, constant productive cough that never goes away. It’s hard to eat while you cough. Fat folks probably had the advantadge of living longer without being able to eat as much. Though I think that before the advent of modern antibiotics TB was pretty much always eventually lethal for everyone. It might also be that because the obese usually have less inspiratory volume the mycobacterium was not able to spread as easily inside the lung.

by brimstone33 on Jun 30, 2009 4:20 PM EDT reply actions  

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