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When Your Belly Becomes a Beast

A new study suggests that a chemical known to regulate appetite can cause your body to act against its own best interests. The science, I confess, is over my head, but this BBC News report gamely attempts an explanation:

The fat that some people carry around their middles could be making them even fatter, researchers have said. The Canadian team found abdominal fat tissue produces a hormone called NPY -- which also prompts the development of cells that turn into fat.

The upshot is that a vicious cycle ensues once visceral fat starts producing neuropeptide Y: You get hungrier, you eat more, and you're more likely to store that excess food in these new fat cells accumulating in your midsection.

The news report concludes with hope for a new drug to slow down or reverse this process:

Dr. Yang added: "If you can detect NPY early and identify those at risk for abdominal obesity we can then target therapy to turn off NPY. It would be much easier to use drugs to prevent obesity than to treat the diseases caused by obesity."

I guess that's true. But what happens if you intervene even earlier, and use diet, exercise, and lifestyle changes to prevent that accumulation of abdominal fat in the first place? Wouldn't that nip the entire process in the bud?

Thursday blog meat

  • According to a new survey, people get happier as they grow older. Which reminds me of something I saw in the latest issue of The Atlantic: Unhappiness peaks at age 49 for men, and at 45 for women. (Here's that study's abstract.)
  • This is interesting: When a type of fish is overharvested, the species goes into evolutionary overdrive. Younger, smaller fish -- the ones that get left behind they aren't worth anything to the fishing industry -- mature faster, and show evidence of rapid changes at the genetic level. Wouldn't this actually explain a lot about human evolution, particularly the rapid emergence of modern humans? If earlier humans were being hunted by the top predators of the time, then the few that survived would have included those best able to think in new ways, to form strategies that went beyond searching for the next day's meals. That would require more complex language, along with the invention of representational art to show what those plans might look like in action. If this extrapolation I just totally pulled out of my ass is correct, sometime in the next 50,000 years we should see fish arguing about politics and diagramming football plays on the ocean floor.

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Evolutionary Overdrive
It seems to me, the top predators of humans have always been humans.  If so, taking this theory to its logical end, it seems warfare would promote the types of changes in humans that are observed in fish.  

by Joe in DC on Apr 17, 2008 10:34 AM EDT   0 recs

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